Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity connected to bortezomib, a proteasome inhibitor Employed in the cure of many myeloma. Its synthesis or examine is crucial for making sure the purity and basic safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound in the synthesis of imatinib, a drug that targets certain kinds of most cancers, which includes Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the manufacturing approach and ensuring substantial purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to take care of breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist GeMcitabine Intermediate 8 used in the treatment method of breast most cancers. Various intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment method of colorectal most cancers and modest mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have many purposes, such as antiviral Houses.
Vildagliptin Intermediates: Employed in the creation lapatinib intermediate of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of various gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication employed to handle sort 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).